Post Market Analysis of Some Neem Products Sold in Nigeria

Pharmacognosy Research,2022,14,2,211-218.DOI:10.5530/pres.14.2.30Published:April 2022Type:Original ArticleAuthors:Obi Peter Adigwe, Omolola Temitope Fatokun, Kevwe Benefit Esievo, Aliyu Adamu, Kazeem Olatunji, Jemilat Ibrahim, and Kudirat Bolanle Mustapha Author(s) affiliations:Obi Ibrahim*, Department of Medicinal Plant Research Traditional Medicine, National Institute for Pharmaceutical Medicine Idu, Industrial Area, F.C.T. Abuja, NIGERIA. Abstract:Context: The wide acceptability herbal medicines as finished products is hindered by the lack quality control profile total trust in purity, safety efficacy identity product. Aim: study evaluated pharmacognostic, physicochemical, chromatographic properties microbial load commercially packaged neem Nigeria towards ascertaining its identity, content purity. Settings Design: Finished were randomly purchased from different market sources tested compliance to already established standards documented WHO, NHP, WAHP USP. Materials Methods: macroscopic, microscopic, physicochemical using standard procedures. Chemical-markers such rutin quercetin quantified a validated HPLC method. Microbiological (bacterial fungal counts) assessed according USP WHO methods guidelines. Descriptive statistics was used study. Results represented percentages mean with respect deviation where appropriate. Results: Macroscopic microscopic evaluations showed absence adulterants foreign matter presence characteristic features Azadirachta indica. Physico-chemical tests depicted varying results indicating differing collection possible soil types. Conclusion: macro, chemical microbiological checks identification purity have been established. contained primarily indica considered safe consumption. obtained are beneficial enriching current monographs commercialization. Key words: Pharmacognostic, Microscopy, Microbial load, Validation, HPLC. View:PDF (507.91 KB)